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Twelve Weeks of Recovery Enhancement with Combat Creatine

A Double-Blind, Placebo-Controlled Pilot Study

📄 Abstract

Background: Creatine is widely recognized for enhancing strength and muscle performance. However, its impact on neuromuscular and autonomic recovery—especially when combined with nootropics and adaptogens—has not been well studied.

Objective: To evaluate the effects of Combat Creatine, a multi-ingredient supplement, on subjective and physiological recovery over 12 weeks of resistance training.

Methods: 40 trained athletes were randomly assigned to receive either Combat Creatine or placebo. Weekly recovery was measured via a 10-point scale and HRV tracking via WHOOP.

Result Highlight: Recovery scores in the Combat Creatine group improved from 5.1 to 9.2 (p < 0.001), while placebo only rose to 6.3. HRV also increased significantly in the intervention group.

Conclusion: Combat Creatine significantly enhanced systemic recovery, supporting its use as a daily supplement for performance and regeneration.

Keywords: Creatine, HRV, DOMS, Recovery, Adaptogens, Nootropics, Athletic Performance

1️⃣ Introduction

Recovery is not just about reducing soreness—it involves muscle repair, central nervous system reset, and rebalancing hormonal and cellular functions. Combat Creatine is designed to support this process with a scientifically backed blend of performance and neuro-recovery compounds. This study aims to quantify its effectiveness compared to placebo.

2️⃣ Methods

2.1 Study Design

40 trained men and women (ages 21–38) were enrolled in a double-blind, placebo-controlled, 12-week trial. All participants followed a standardized strength training program (4x/week).

2.2 Intervention Details

Combat Creatine included the following per serving:

  • Creatine Monohydrate (5 g)
  • Acetyl-L-Carnitine (1 g)
  • Rhodiola Rosea (600 mg)
  • Ashwagandha KSM-66® (600 mg)
  • Alpha-GPC (600 mg), CDP-Choline (600 mg)
  • Magnesium L-Threonate (300 mg)

Control group received a flavor-matched placebo.

2.3 Measurements

Primary outcome: Weekly self-reported 10-point recovery scale.

Secondary outcomes: HRV via WHOOP, DOMS scores, training session adherence.

3️⃣ Results

3.1 Subjective Recovery

Combat Creatine: Recovery score rose from 5.1 → 9.2 (p < 0.001)
Placebo: Recovery rose from 5.0 → 6.3 (p < 0.05)

3.2 HRV (Heart Rate Variability)

Participants using Combat Creatine experienced a 19.8% increase in RMSSD (p = 0.002), suggesting improved parasympathetic nervous system activity. Placebo group showed no significant HRV change.

3.3 DOMS and Adherence

Combat Creatine group reported:

  • 25% less soreness by week 8 (p < 0.01)
  • 96% training compliance vs. 87% in placebo

4️⃣ Discussion

The synergistic effects of ingredients in Combat Creatine created a powerful recovery advantage. The following mechanisms are believed to contribute:

  • Phosphocreatine resynthesis: Recharges ATP, accelerating recovery
  • Cell hydration & osmotic pressure: Supports mTOR signaling for muscle growth
  • Adaptogenic stress control: Ashwagandha and Rhodiola reduced CNS fatigue
  • Neurorecovery: Choline donors enhanced mental clarity and mood

This data underscores creatine’s expanding role in athletic recovery—particularly when paired with high-potency cognitive and adaptogenic ingredients.

5️⃣ Conclusion

Combat Creatine significantly outperformed placebo in supporting full-system recovery. Its effect on HRV, perceived recovery, and soreness reduction demonstrates its value for serious athletes seeking recovery edge.

Recommendation: Future research should investigate Combat Creatine’s role in overtraining syndrome prevention, cognitive fatigue, and stress resilience.

Conflict of Interest: This study was conducted independently. No financial conflicts reported.

📚 References

1. Kreider RB et al. Int J Sport Nutr Exerc Metab. 2017.

2. Rawson ES, Volek JS. J Strength Cond Res. 2003.

3. Laurent CM et al. J Strength Cond Res. 2011.

4. Greenhaff PL et al. Am J Physiol. 1993.

5. Cooke MB et al. J Sports Med Phys Fitness. 2009.

6. Safdar A et al. J Physiol. 2008.

7. Panossian A, Wikman G. Curr Clin Pharmacol. 2010.

" tabindex="0"> Combat Creatine Clinical Study

Twelve Weeks of Recovery Enhancement with Combat Creatine

A Double-Blind, Placebo-Controlled Pilot Study

📄 Abstract

Background: Creatine is widely recognized for enhancing strength and muscle performance. However, its impact on neuromuscular and autonomic recovery—especially when combined with nootropics and adaptogens—has not been well studied.

Objective: To evaluate the effects of Combat Creatine, a multi-ingredient supplement, on subjective and physiological recovery over 12 weeks of resistance training.

Methods: 40 trained athletes were randomly assigned to receive either Combat Creatine or placebo. Weekly recovery was measured via a 10-point scale and HRV tracking via WHOOP.

Result Highlight: Recovery scores in the Combat Creatine group improved from 5.1 to 9.2 (p < 0.001), while placebo only rose to 6.3. HRV also increased significantly in the intervention group.

Conclusion: Combat Creatine significantly enhanced systemic recovery, supporting its use as a daily supplement for performance and regeneration.

Keywords: Creatine, HRV, DOMS, Recovery, Adaptogens, Nootropics, Athletic Performance

1️⃣ Introduction

Recovery is not just about reducing soreness—it involves muscle repair, central nervous system reset, and rebalancing hormonal and cellular functions. Combat Creatine is designed to support this process with a scientifically backed blend of performance and neuro-recovery compounds. This study aims to quantify its effectiveness compared to placebo.

2️⃣ Methods

2.1 Study Design

40 trained men and women (ages 21–38) were enrolled in a double-blind, placebo-controlled, 12-week trial. All participants followed a standardized strength training program (4x/week).

2.2 Intervention Details

Combat Creatine included the following per serving:

  • Creatine Monohydrate (5 g)
  • Acetyl-L-Carnitine (1 g)
  • Rhodiola Rosea (600 mg)
  • Ashwagandha KSM-66® (600 mg)
  • Alpha-GPC (600 mg), CDP-Choline (600 mg)
  • Magnesium L-Threonate (300 mg)

Control group received a flavor-matched placebo.

2.3 Measurements

Primary outcome: Weekly self-reported 10-point recovery scale.

Secondary outcomes: HRV via WHOOP, DOMS scores, training session adherence.

3️⃣ Results

3.1 Subjective Recovery

Combat Creatine: Recovery score rose from 5.1 → 9.2 (p < 0.001)
Placebo: Recovery rose from 5.0 → 6.3 (p < 0.05)

3.2 HRV (Heart Rate Variability)

Participants using Combat Creatine experienced a 19.8% increase in RMSSD (p = 0.002), suggesting improved parasympathetic nervous system activity. Placebo group showed no significant HRV change.

3.3 DOMS and Adherence

Combat Creatine group reported:

  • 25% less soreness by week 8 (p < 0.01)
  • 96% training compliance vs. 87% in placebo

4️⃣ Discussion

The synergistic effects of ingredients in Combat Creatine created a powerful recovery advantage. The following mechanisms are believed to contribute:

  • Phosphocreatine resynthesis: Recharges ATP, accelerating recovery
  • Cell hydration & osmotic pressure: Supports mTOR signaling for muscle growth
  • Adaptogenic stress control: Ashwagandha and Rhodiola reduced CNS fatigue
  • Neurorecovery: Choline donors enhanced mental clarity and mood

This data underscores creatine’s expanding role in athletic recovery—particularly when paired with high-potency cognitive and adaptogenic ingredients.

5️⃣ Conclusion

Combat Creatine significantly outperformed placebo in supporting full-system recovery. Its effect on HRV, perceived recovery, and soreness reduction demonstrates its value for serious athletes seeking recovery edge.

Recommendation: Future research should investigate Combat Creatine’s role in overtraining syndrome prevention, cognitive fatigue, and stress resilience.

Conflict of Interest: This study was conducted independently. No financial conflicts reported.

📚 References

1. Kreider RB et al. Int J Sport Nutr Exerc Metab. 2017.

2. Rawson ES, Volek JS. J Strength Cond Res. 2003.

3. Laurent CM et al. J Strength Cond Res. 2011.

4. Greenhaff PL et al. Am J Physiol. 1993.

5. Cooke MB et al. J Sports Med Phys Fitness. 2009.

6. Safdar A et al. J Physiol. 2008.

7. Panossian A, Wikman G. Curr Clin Pharmacol. 2010.